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Application number: P.437038 (17.02.2021)
Patent number:
Patent inventors: Grażyna Hoser, Iga Stukan, Marek Gryzik, Mikołaj Zdioruk, Marcin Cieślak, Mariola Napiórkowska, Karolina Królewska-Golińska, Barbara Nawrot, Urszula Wojda

Description of the invention will be available after the patent application is published.

Application number: P.434449 (25 Jun 2020)
Patent number:
Patent inventors: Bartosz Frycz, Marzena Stefaniuk, Klaudia Nowicka, Leszek Kaczmarek

Description of the invention will be available after the patent application is published.

Application number: P.434336 (16 Jun 2020)
Patent number:
Patent inventors: Adam Gorlewicz, Leszek Kaczmarek

Description of the invention will be available after the patent application is published.

Application number: P.423173 (16 Oct 2017)
Patent number: PL 233602 (09 Jul 2019)
Patent inventors: Łukasz Bożycki, Kacper Łukasiewicz, Paweł Matryba

Patent was granted in Poland and Nencki Institute is the sole applicant.

Application number: P.415290 (14 Dec 2015), PCT/IB2015/002333 (14 Dec 2015)
Patent number: PL235340 (02 Mar 2020)
Patent inventors: Katarzyna Konarzewska, Małgorzata Zawadzka

The subject of the present invention is a method for detecting active, remyelinating lesions in patients diagnosed with multiple sclerosis through the determination of changes in the levels of interleukin-33 in peripheral blood and cerebrospinal fluid, which constitutes a novel marker of endogenous repair processes facilitating the monitoring of the differentiation of oligodendrocyte precursor differentiation…

Application number: P.414469 (23 Oct 2015), PCT/IB2015/059225 (30 Nov 2015)
Patent number: PL234915 (22 Jan 2020)
Patent inventors: Magdalena Pawlak, Agnieszka Kikulska, Tomasz Wilanowski, Joanna Wesoły, Bartosz Wilczyński

The present invention relates to methods for the identification of single nucleotide polymorphisms (SNP) in the GRHL1, GRHL2 and GRHL3 genes and the use of these polymorphisms as markers to identify patients at increased susceptibility to cancer of the kidneys.

Application number: P.411390 (26 Feb 2015), PCT/IB2016/051087 (26 Feb 2016), EP16714534.1 (26 Feb 2016), US 15553575 (26 Feb 2016)
Patent number: US 10222384 (05 Mar 2019), EP 3262420 (20 Mar 2019)
Patent inventors: Agnieszka Dobrzyń, Paweł Dobrzyń, Kamil Koziński, Tomasz Bednarski

The invention relates to the diagnosis of the pre-diabetoc state and processes underlying development of diabetic state way before blood glucose levels are abnormaln and diabetes clinical symptoms occur.  This may be done using the relative proportion of the level of the Wnt4 and Wnt3a proteins in blood plasma. wew ew Briefly, in prediabetic state…

Application number: P.410001 (14 Nov 2014), PCT/PL2015/050058 (04 Nov 2015)
Patent number: PL 224680 (31 Jan 2017)
Patent inventors: Kacper Łukasiewicz, Magdalena Robacha, Marzena Stefaniuk, Artur Wolny, Katarzyna Radwańska

A device (1) for immobilizing an animal in order to examine a selected area of the animal’s body, the device (1) comprising two upright members (2a, 2b) secured by their lower ends to a base (3), the height of the upright members (2a, 2b) being adjustable independently of one another and being adapted to be…

Application number: MI2013A002141 (19 Dec 2013), P.410049 (03 Nov 2014), PCT/PL2014/0500078 (19 Dec 2014), USA 15106163 (19 Dec 2014), AU 20140367369 (19 Dec 2014), EP 14835533.2 (19 Dec 2014)
Patent number: US 10000816 (19 Jun 2018), EP 3083999 (05 Jun 2019), AU 2014367369 (09 Jul 2020)
Patent inventors: Agnieszka Kikulska, Tomasz Wilanowski, Piotr Rutkowski

This invention relates generally to the field of cancer diagnostics, and in particular to the detection of an increased risk of developing a skin cancer. Specifically, the present invention relates to a method of detecting and identifying an increased risk of developing a skin cancer in a human patient based on polymorphisms of the GRHL3…

Application number: P.405046 (12 Aug 2013), PCT/IB2014/063883 (12 Aug 2014), CN201480047715.0 (12 Aug 2014), EP 20140789607 (12 Aug 2014), JP 2016-533982 (12 Aug 2014), US 14911821 (12 Aug 2014)
Patent number: US 9914955 (13 Mar 2018)
Patent inventors: Michał Stawarski, Jakub Włodarczyk, Leszek Kaczmarek

The present invention relates to a genetically encoded FRET-based biosensor to monitor the activity of matrix metalloproteinase 9 (MMP-9). MMP-9 is an extracellular acting endopeptidase implicated in both physiological and pathological processes. A genetically encoded FRET biosensor anchored in the cellular membrane allows studying the proteolytic activity of MMP-9 with high spatiotemporal resolution at the…

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